NUCLEAR MEDICINE 核医学(英文原版改编版)(留学生与双语教学用) 下载 pdf 百度网盘 epub 免费 2025 电子版 mobi 在线

每年来华的医学留学生人数增加，招生量扩大，留学生用的性价比合适的教材需求越来越迫切。而现在没有全国性编写的成套教材可供选择，出版后对*系列教材建设是一个完善和补充，对参编院校的理论建设教材体系也是一个契机和提升。

随着核医学显像设备SPECT及PET的逐步普及应用，核医学与临床各学科的关系日趋密切。核医学分子影像成为影像诊断中不可或缺的部分。该教材除了注重核医学基础理论、基本技术及核医学在各系统的临床应用外，重点按系统编写，内容主要根据临床实用与需要考虑。为加深学生对核医学影像的认识和理解，精选大量原始彩色插图，深入浅出，让读者易懂易学。此外，也突出了核素治疗在临床核医学中的重要地位，体现出临床核医学是一门诊断与治疗并重的学科。

Contents

目录

PartⅠ　Basic Principles

Chapter 1 Physics of Nuclear Medicine 3

RADIoACTIvITY AND RADIoACTIvE DECAY  3

INTERACTIoNS BETWEEN RADIATIoN AND MATTER  7

SUGGESTED READING  12

Chapter 2 Radiopharmaceuticals  13

ElEMENTS, RADIoNUClIDES, AND RADIoPHARMACEUTICAlS  13

PRoDUCTIoN oF RADIoNUClIDES  14

RADIoNUClIDE GENERAToRS  15

TECHNETIUM CHEMISTRY AND RADIoPHARMACEUTICAl PREPARATIoN  16

QUAlITY ASSURANCE oF TECHNETIUM-99M—lABElED RADIoPHARMACEUTICAlS  16

SINGlE-PHoToN RADIoPHARMACEUTICAlS oTHER THAN TC-99M  17

DUAl PHoToN RADIoPHARMACEUTICAlS FoR PoSITRoN EMISSIoN ToMoGRAPHY  18

DISPENSING RADIoPHARMACEUTICAlS  18

SUGGESTED READING  19

Chapter 3 Radiation Detection and Instrumentation  20

CHARATERISTICS oF A RADIATIoN DETECToR  20

TYPES oF RADIATIoN DETECToRS  21

ANCIllARY EQUIPMENT  22

NUClEAR MEDICINE IMAGING  23

SUMMARY  27

SUGGESTED READING  28

Chapter 4 Single-Photon Emission Computed Tomography, Positron

Emission Tomography, and Hybrid Imaging  29

 IMAGE RECoNSTRUCTIoN  29

SINGlE-PHoToN EMISSIoN CoMPUTED ToMoGRAPHY  35

PoSITRoN EMISSIoN ToMoGRAPHY  35

 HYBRID PoSITRoN EMISSIoN

CoMPUTED ToMGRAPHY, SINGlEPHoToN CoMPUTED ToMoGRAPHY WITH CoMPUTED ToMoGRAPHY,

AND PoSITRoN EMISSIoN ToMoGRAPHY WITH MAGNETIC RESoNANCE  36 SUGGESTED READING  37

Chapter 5 Molecular Imaging  38

IMAGING TECHNIQUES  38

BIoMARkERS  39

REPoRTER GENE IMAGING AND GENE THERAPY  42

SUGGESTED READING  43

Part Ⅱ　Clinical Nuclear Medicine

Chapter 6 Central Nervous System  47

CEREBRAl ANAToMY  47

CEREBRAl BlooD FloW AND METABolISM  48

ClINICAl APPlICATIoNS FoR CEREBRAl PERFUSIoN IMAGING  51

MovEMENT DISoRDERS  62

AMYloID IMAGING  63

CISTERNoGRAPHY  64

SUGGESTED READING  68

Chapter 7 Cardiac System  69

MYoCARDIAl PERFUSIoN SCINTIGRAPHY  69

PoSITRoN EMISSIoN ToMoGRAPHY oF THE HEART  97

RADIoNUClIDE vENTRICUloGRAPHY  104

MYoCARDIAl INFARCT AND AMYloIDoSIS IMAGING  111

SUGGESTED READING  111

Chapter 8 Endocrine System  113

THYRoID SCINTIGRAPHY AND UPTAkE STUDIES  113

PARATHYRoID SCINTIGRAPHY  121

SUGGESTED READING  124

Chapter 9 Oncology: Positron Emission Tomography  125

BACkGRoUND  125

IMAGE INTERPRETATIoN  127

ClINICAl USES oF PoSITRoN EMISSIoN ToMoGRAPHY IN oNColoGY  134

SUGGESTED READING  151

Chapter 10 Oncology: Non–Positron Emission Tomography  152

PEPTIDE RECEPToR IMAGING  152

ADRENAl SCINTIGRAPHY  154

MoNoCloNAl ANTIBoDY IMAGING AND THERAPY  156

NoNSPECIFIC BINDING TUMoR AGENTS  160

lYMPHoSCINTIGRAPHY: THE SENTINEl lYMPH NoDE  162

INTRAARTERIAl RADIoACTIvE MICRoSPHERES  164

BoNE PAIN PAllIATIoN  165

SUGGESTED READING  167

Chapter 11 Skeletal Scintigraphy  169

BoNE SCAN  169

ClINICAl APPlICATIoN oF SkElETAl SCINTIGRAPHY  176

BoNE INFARCTIoN AND oSTEoNECRoSIS  191

oSTEoMYElITIS  193

FloURINE-18 SoDIUM FlUoRIDE PoSITRoN EMISSIoN ToMoGRAPHY  196

BoNE MINERAl MEASUREMENT  197

SUGGESTED READING  198

Chapter 12 Pulmonary System  199

PUlMoNARY EMBolISM  199

vENTIlATIoN PERFUSIoN SCINTIGRAPHY  199

RADIoPHARMACEUTICAlS  200

IMAGE INTERPRETATIoN  203

vENTIlATIoN-PERFUSIoN INTERPRETATIoN CRITERIA  207

oTHER ADDITIoNAl v/Q INTERPRETATIoN CRITERIA  212

SUGGESTED READING  212

Chapter 13 Infection and Inflammation  213

RADIoPHARMACEUTICAlS  213

ClINICAl APPlICATIoNS FoR INFECTIoN SCINTIGRAPHY  218

SUGGESTED READING  226

Chapter 14 Gastrointestinal System  227

ESoPHAGEAl MoTIlITY  227

GASTRoESoPHAGEAl REFlUX DISEASE  230

GASTRIC MoTIlITY SCINTIGRAPHY  231

INTESTINAl TRANSIT SCINTIGRAPHY  237

PRoTEIN-loSING ENTERoPATHY  239

HElICoBACTER PYloRI INFECTIoN  239

GASTRoINTESTINAl BlEEDING  239

HETERoToPIC GASTRIC MUCoSA  245

SUGGESTED READING  248

Chapter 15 Hepatobiliary System  249

CHolESCINTIGRAPHY  249

TECHNETIUM-99M RED BlooD CEll lIvER SCINTIGRAPHY  267

TECHNETIUM-99M SUlFUR ColloID lIvER AND SPlEEN IMAGING  270

SPlEEN SCINTIGRAPHY  272

TECHNETIUM-99M MACRoAGGREGATED AlBUMIN HEPATIC ARTERIAl PERFUSIoN

SCINTIGRAPHY  274

SUGGESTED READING  275

Chapter 16 Genitourinary System  277

RENAl ANAToMY AND FUNCTIoN  277

RENAl RADIoPHARMACEUTICAlS  278

DYNAMIC RENAl IMAGING TECHNIQUES  283

 MEASURING RENAl

FUNCTIoN:EFFECTIvE RENAl PlASMA FloW(ERPF)AND GloMERUlAR

FIlTRATIoN RATE (GFR)  292

RENAl CoRTICAl IMAGING  292

SUGGESTED READING  294

Part Ⅲ　Radionuclide Therapy Chapter 17

Nuclear Medicine Therapy  297

RADIoIoDINE THEARPY FoR HYPERTHYRoIDISM  297

MANAGEMENT oF HYPERTHYRoIDISM DUE To ToXIC MUlTINoDUlAR GoITER AND

ToXIC

ADENoMA  300

MANAGEMENT oF GD IN CHIlDREN AND ADolESCENTS  301

CANCER RISk AND RADIATIoN SAFETY REGARDING RADIoIoDINE THEARPY FoR

HYPERTHYRoIDISM  301

RADIoIoDINE THERAPY FoR THYRoID CANCER  302

METASTATIC BoNE PAIN THERAPY  309

SUGGESTED READING  311

谭建、教授、博士研究生导师，核医学科主任，核医学教研室主任。现任中华医学会核医学分会常委，中华医学会核医学分会肿瘤学组组长。中国医师协会核医学医师分会常委，中国医师学会核医学医师分会医师培训与考核委员会副主任。中国影像技术研究会核医学分会副主任委员。天津医学会核医学分会主委。

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Basic Principles 

Chapter 1 

Physics of Nuclear Medicine 

Nuclear medicine involves the administration of 160 radiopharmaceuticals to patients for diagnostic and therapeutic purposes. For diagnostic imaging, 140 radiation emitted from these radiopharmaceuticals must be detected by external detectors to determine 120 its in vivo distribution. For therapeutic nuclear medicine, some of the emitted radiation must be 100 absorbed by targeted tissues to achieve the desired effect. In both cases, an understanding of the nature of the radioactivity, the amount administered, the radiation emissions, and how it interacts with matter is essential. The essential aspects of the basic physics 

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编辑推荐

本教材为留学生临床医学专业用教材系列之一，原版引进改编，国内*本。

书摘插图

前言

The applications of Nuclear Medicine in

different medical disciplines have kept increasing in the past several decades.

As an important part of molecular imaging, SPECT/CT and PET/ CT have become

commonly used in Nuclear Medicine imaging modality. Nuclear Medicine, as an

important medical knowledge, has been independently and widely learned by

medical students including overseas students. More and more overseas students

come to China to learn medicine in recent years. Most of them apply for

Bachelor’ degree. It is necessary to edit an English textbook of Nuclear

Medicine for the undergraduate program. Physicians from Nuclear Medicine

department of Tianjin Medical University General Hospital have been devoted to

Nuclear Medicine education since the 1980s. Supported and organized by Tsinghua

University Press and Tianjin Medical University, twelve Nuclear Medicine

experts and scholars from nine universities in China make contributions to this

textbook, which is based on Nuclear Medicine The requisites(edition 4) written

by Harvey A. Ziessman MD and published by Saunders.

In order to meet the basic needs of both

international and domestic medical students, necessary adaptations and

revisions are carefully made from the original book. In addition, we reorganize

the chapters and make a new chapter of radionuclide therapy in order to give

students a systemic knowledge in this field. This new textbook covers three

parts, including Basic Principles, Clinical Nuclear Medicine and Radionuclide

Therapy. The chapters follow an outline format and the main section (Clinical

Nuclear Medicine) are divided by organ-systems (i.e., Central Nervous System,

Cardiac System, Endocrine System, etc).

Although this edition is primarily designed

for overseas medical students, it is also a good reference book for Nuclear

Medicine physicians and technicians, resident doctors in other specialties. We

hope it is helpful to all the readers. We would like to share our limited

knowledge and experience with the readers. Comments and suggestions for this

book are always welcome.

In compiling this book, we received

assistance from many sources, and would like to thank those people for their

supports.

Editors July 8,2017